-
Christian Schiffer authored0af4afa2
bigbrain.json 41.22 KiB
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"name": "Cortical Layers Segmentation",
"description": "The cerebral isocortex has six cytoarchitectonic layers that vary depending on cortical area and local morphology. This datasets provides a 3D segmentation of all cortical and laminar surfaces in the BigBrain, a high-resolution, 3D histological model of the human brain. The segmentation has been computed automatically based on histological intensities along 3D cortical profiles which were sampled between the pial and white matter throughout the dataset. These cortical profiles were segmented into layers using a convolutional neural network. Training profiles were generated from examples of manually segmented layers on cortical regions from 2D histological sections of the BigBrain. From the segmented intensity profiles, surface meshes and voxel masks of all six cortical layers in the space of the Big Brain have been computed.",
"publications": [
{
"doi": "https://doi.org/10.1101/580597",
"cite": "Konrad Wagstyl, Stéphanie Larocque, Guillem Cucurull, Claude Lepage, Joseph Paul Cohen, Sebastian Bludau, Nicola Palomero-Gallagher, Thomas Funck, Hannah Spitzer, Timo Dicksheid, Paul C Fletcher, Adriana Romero, Karl Zilles, Katrin Amunts, Yoshua Bengio, Alan C. Evans (2019) Automated segmentation of cortical layers in BigBrain reveals divergent cortical and laminar thickness gradients in sensory and motor cortices. bioRxiv 580597; doi: https://doi.org/10.1101/580597"
}
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"displayName": "Isocortex",
"type": "parcellation",
"ngData": null,
"ngId": " tissue type: ",
"regions": [
{
"name": "Isocortex",
"labelIndex": 100,
"rgb": [
200, 200,
200
],
"children": []
},
{
"name": "Non-isocortical structures",
"labelIndex": 200,
"rgb": [
255,
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],
"children": []
}
]
}
],
"properties": {
"name": "Big Brain (Histology)",
"description": "A microscopic resolution 3D model of a complete human brain, based on a 3D reconstruction from 7404 digitized histological brain sections (Amunts, Evans et al., Science 2013). The BigBrain model provides a highly detailed anatomical reference space which resolves individual cortical layers and large cell bodies. Maps of cytoarchitectonic areas (Amunts et al.) and cortical layers (Wagstyl et al.) are available.",
"publications": [
{
"doi": "10.1126/science.1235381",
"cite": "K. Amunts, A. Evans et al.: BigBrain: An Ultrahigh-Resolution 3D Human Brain Model. Science 2013"
},
{
"doi": "http://bigbrain.loris.ca",
"cite": "http://bigbrain.loris.ca"
}
]
}
}