diff --git a/packages/py-biobb-analysis/package.py b/packages/py-biobb-analysis/package.py
index 799d4c36cff2f43075cba01cb23a707d58dde4a7..9c580af04384d385d1539d04ad91d5afd4cec188 100644
--- a/packages/py-biobb-analysis/package.py
+++ b/packages/py-biobb-analysis/package.py
@@ -12,14 +12,13 @@ class PyBiobbAnalysis(PythonPackage):
     # Homepage and download url
     homepage = "https://github.com/bioexcel/biobb_analysis"
     git = 'https://github.com/bioexcel/biobb_analysis.git'
-    url = 'https://github.com/bioexcel/biobb_analysis/archive/refs/tags/v4.0.1.tar.gz'
+    url = 'https://github.com/bioexcel/biobb_analysis/archive/refs/tags/v4.1.0.tar.gz'
 
     # Set the gitlab accounts of this package maintainers
     maintainers = ['dbeltran']
 
     # Versions
-    version('master', branch='master')
-    version('4.0.1', sha256='3d7190d0cae6af42b2e7c0ecf073930a609b699ef311e8b74afc1634958e09b0')
+    version('4.1.0', sha256='fecbb7ffa0e38f732fcc613adc7f1656e3c65af519a072269dabc244681f1791')
 
     # Dependencies
     depends_on('python@3.8:', type=('build', 'run'))
@@ -27,16 +26,6 @@ class PyBiobbAnalysis(PythonPackage):
     depends_on('gromacs')
     depends_on('ambertools')
 
-    # Patching to enable python 3.10 (not official, might not be stable)
-    def patch(self):
-        filter_file("    python_requires='>=3.7,<3.10',", "    python_requires='>=3.7,<3.11',", "setup.py")
-        filter_file(
-            "'Programming Language :: Python :: 3.9'",
-            "'Programming Language :: Python :: 3.9',\r\n        "
-            "'Programming Language :: Python :: 3.10'",
-            "setup.py",
-        )
-
     # Test
     @run_after('install')
     @on_package_attributes(run_tests=True)
diff --git a/packages/py-biobb-chemistry/package.py b/packages/py-biobb-chemistry/package.py
index 6ec163b67d6743ac31711a1f3a6b7253738a4246..c30b809245e1e2161716bc65aff4a2b1798e5638 100644
--- a/packages/py-biobb-chemistry/package.py
+++ b/packages/py-biobb-chemistry/package.py
@@ -12,14 +12,13 @@ class PyBiobbChemistry(PythonPackage):
     # Homepage and download url
     homepage = "https://github.com/bioexcel/biobb_chemistry"
     git = 'https://github.com/bioexcel/biobb_chemistry.git'
-    url = 'https://github.com/bioexcel/biobb_chemistry/archive/refs/tags/v4.0.0.tar.gz'
+    url = 'https://github.com/bioexcel/biobb_chemistry/archive/refs/tags/v4.1.0.tar.gz'
 
     # Set the gitlab accounts of this package maintainers
     maintainers = ['dbeltran']
 
     # Versions
-    version('master', branch='master')
-    version('4.0.0', sha256='40f65b4a93dff24e19995265e41fd6821f5ac2f35199d938f1d00fa035883e64')
+    version('4.1.0', sha256='8d04943bbfcd83eb4d5d3247949cf035977fd097d5014a39354b0502e1cd16c8')
 
     # Dependencies
     depends_on('python@3.8:', type=('build', 'run'))
@@ -28,16 +27,6 @@ class PyBiobbChemistry(PythonPackage):
     depends_on('ambertools')
     depends_on('acpype')
 
-    # Patching to enable python 3.10 (not official, might not be stable)
-    def patch(self):
-        filter_file("    python_requires='>=3.7,<3.10',", "    python_requires='>=3.7,<3.11',", "setup.py")
-        filter_file(
-            "'Programming Language :: Python :: 3.9'",
-            "'Programming Language :: Python :: 3.9',\r\n        "
-            "'Programming Language :: Python :: 3.10'",
-            "setup.py",
-        )
-
     # Test
     @run_after('install')
     @on_package_attributes(run_tests=True)
diff --git a/spack.yaml b/spack.yaml
index c6d455fd5367bfb0b8999ff6348050a81cd83897..9d86fd2f892c22cac654c159cf7666e584f16cab 100644
--- a/spack.yaml
+++ b/spack.yaml
@@ -4,8 +4,8 @@ spack:
   specs:
     # EBRAINS tools
     - arbor@0.10.0 +python +mpi
-    - py-biobb-analysis@4.0.1
-    - py-biobb-chemistry@4.0.0
+    - py-biobb-analysis@4.1.0
+    - py-biobb-chemistry@4.1.0
     - py-biobb-common@4.1.0
     - py-biobb-gromacs@4.1.1
     - py-biobb-io@4.1.0