diff --git a/macosx/Portfile b/macosx/Portfile
new file mode 100644
index 0000000000000000000000000000000000000000..555e5213beac083c4705012f9ff70d87522afde5
--- /dev/null
+++ b/macosx/Portfile
@@ -0,0 +1,87 @@
+# -*- coding: utf-8; mode: tcl; tab-width: 4; indent-tabs-mode: nil; c-basic-offset: 4 -*- vim:fenc=utf-8:et:sw=4:ts=4:sts=4
+# $Id$
+
+PortSystem              1.0
+PortGroup               python 1.0
+
+name                    moose
+categories-append       science biology chemistry
+version                 3.0.2
+categories              science
+platforms               darwin
+maintainers             dilawars \
+                        ncbs.res.in:dilawars
+description             Neuronal modeling software spanning molecules, electrophysiology \
+                        and networks
+
+long_description        MOOSE is designed to simulate neural systems ranging from \
+                        subcellular components and biochemical reactions to \
+                        complex models of single neurons, circuits, and large networks. \
+                        MOOSE can operate at many levels of detail, from stochastic chemical \
+                        computations, to multicompartment single-neuron models, to spiking neuron \
+                        network models.
+
+homepage                http://moose.ncbs.res.in
+fetch.type              git
+fetch.ignore_sslcert    yes
+git.url                 https://github.com/BhallaLab/moose-full
+git.branch              master
+license                 GPL-3
+
+
+depends_build           port:cmake \
+                        port:python27 \
+                        port:gsl  \
+                        port:hdf5 \
+
+depends_lib-append      port:gsl \
+                        port:hdf5 \
+                        port:py27-numpy \
+                        port:py-pyqt4 \
+                        port:python27 \
+
+depends_run-append      port:py-suds-jurko \
+                        port:py27-matplotlib \
+                        port:python27 \
+                        port:py-networkx \
+
+set python_branch       2.7
+use_configure           yes
+
+
+configure.args          -DCMAKE_INSTALL_PREFIX=${prefix} ..
+configure.post_args     ""
+configure.pre_args      ""
+configure.cmd           mkdir -p _build && cd _build && cmake
+
+build.target            all
+
+build.cmd               cd _build && make
+
+test.run                yes
+test.cmd                cd _build && ctest --output-on-failure
+
+
+destroot.cmd            cd moose-core/python && ${python.bin} setup.py --no-user-cfg
+
+destroot.destdir        --prefix=${python.prefix} --root ${destroot}
+
+post-destroot      {
+
+    set guidir ${prefix}/lib/moose/gui
+    xinstall -m 755 -d ${destroot}${guidir}
+
+    # Replace the $GUIDIR with real path on MacOSX.
+    # TODO: Turn gui subdirectory into a python module.
+    reinplace -W ${worksrcpath}/package_data "s|\$GUIDIR|${guidir}|g" moosegui
+
+    set exampledir ${prefix}/lib/moose/moose-examples
+    xinstall -m 755 -d ${destroot}${exampledir}
+
+    # xinstall does not work recursively. Use rsync to copy the directories.
+    exec rsync -azv ${worksrcpath}/moose-gui/ ${destroot}${guidir}
+    exec rsync -azv ${worksrcpath}/moose-examples/ ${destroot}${exampledir}
+
+    xinstall -m 755 ${worksrcpath}/package_data/moosegui ${destroot}${prefix}/bin/moosegui
+}
+
diff --git a/macosx/brew_moogli.sh b/macosx/brew_moogli.sh
new file mode 100755
index 0000000000000000000000000000000000000000..d960d64ac9559629e68a92a137e12865598e829a
--- /dev/null
+++ b/macosx/brew_moogli.sh
@@ -0,0 +1,14 @@
+#!/bin/bash
+set -x
+
+PATH=/usr/local/bin:$PATH
+
+rm -f /Library/Caches/Homebrew/moogli*.tar.gz
+rm -f /Library/Caches/Homebrew/moogli*.zip
+cp ./moogli.rb /usr/local/Library/Formula/moogli.rb
+
+brew -v install moogli --debug | tee _build_moogli.log
+
+echo "Checking brew script for submission"
+brew audit --strict moogli
+brew -v test moogli
diff --git a/macosx/brew_moose.sh b/macosx/brew_moose.sh
new file mode 100755
index 0000000000000000000000000000000000000000..542a9ed25c056c54c748ec69f3b628fbc733165b
--- /dev/null
+++ b/macosx/brew_moose.sh
@@ -0,0 +1,13 @@
+#!/bin/bash
+set -x
+
+PATH=/usr/local/bin:$PATH
+rm -f /Library/Caches/Homebrew/moose*.tar.gz
+rm -f /Library/Caches/Homebrew/moose*.zip
+cp ./moose.rb /usr/local/Library/Formula/moose.rb
+
+brew -v install moose --with-gui | tee _build_moose.log 
+
+echo "Checking brew script for submission"
+brew audit --strict moose
+brew -v test moose
diff --git a/macosx/moogli.rb b/macosx/moogli.rb
new file mode 100644
index 0000000000000000000000000000000000000000..2206a4d3973ea7b3ed8b1e96752bdf69d55b66d1
--- /dev/null
+++ b/macosx/moogli.rb
@@ -0,0 +1,25 @@
+class Moogli < Formula
+  desc "3d visualizer of neuronal simulation"
+  homepage "http://moose.ncbs.res.in/moogli"
+  url "https://github.com/BhallaLab/moogli/archive/macosx.tar.gz"
+  version "0.5.0"
+
+  depends_on "open-scene-graph"
+  depends_on "python" if MacOS.version <= :snow_leopard
+  depends_on "sip"
+  depends_on "pyqt"
+
+  def install
+    ENV['CFLAGS'] = ""
+    ENV['CXXFLAGS'] = ""
+    # Copy QtCore.so etc to lib of our app.
+    system "./build_on_macosx.sh"
+    system "python", "setup.py", "install", "--prefix", prefix
+    (prefix/"lib/python2.7/site-packages/moogli/core").install "moogli/core/_moogli.so"
+  end
+
+  test do
+    system "#{HOMEBREW_PREFIX}/bin/python", "-c", "import moogli"
+    system "python", "-c", "import moogli"
+  end
+end
diff --git a/macosx/moose.rb b/macosx/moose.rb
new file mode 100644
index 0000000000000000000000000000000000000000..4b2e313d39cbb049b48dabebc6bcb195da1e07fb
--- /dev/null
+++ b/macosx/moose.rb
@@ -0,0 +1,67 @@
+class Moose < Formula
+  desc "Multiscale Object Oriented Simulation Environment"
+  homepage "http://moose.ncbs.res.in"
+  url "https://github.com/BhallaLab/moose-full/archive/master.tar.gz"
+  version "3.0.2"
+
+  option "with-gui", "Enable gui support"
+
+  depends_on "cmake" => :build
+  depends_on "gsl"
+  depends_on "hdf5"
+
+  depends_on "matplotlib" => :python
+  depends_on "python" if MacOS.version <= :snow_leopard
+
+  depends_on "pyqt" => :recommended
+
+  def install
+    args = std_cmake_args
+    args << "-DWITH_SBML=ON"
+
+    # Use libsbml-5.9.0 which is shipped with moose. Use static linking
+    # mechanism. DO NOT rely on macport version.
+    # if build.with?("libsbml")
+    #   args << "-DWITH_SBML=ON"
+    # end
+
+    mkdir "_build" do
+      system "cmake", "..", *args
+      system "make"
+    end
+
+    Dir.chdir("moose-core/python") do
+      system "python", *Language::Python.setup_install_args(prefix)
+    end
+
+    if build.with?("gui")
+      (lib/"moose").install "moose-gui"
+      (lib/"moose").install "moose-examples"
+
+      # A wrapper script to launch moose gui. Do we need to set PYTHONPATH here,
+      # when prefix is not /usr/local?
+      (bin/"moosegui").write <<-EOS.undent
+        #!/bin/bash
+        GUIDIR="#{lib}/moose/moose-gui"
+        (cd ${GUIDIR} && python mgui.py)
+      EOS
+      chmod 0755, bin/"moosegui"
+    end
+  end
+
+  def caveats
+    <<-EOS.undent
+    Please install python-networkx and python-suds-jurko using pip to complete
+    the dependencies.
+
+    $ pip install networkx suds-jurko
+
+    EOS
+  end
+
+  test do
+    ## This will not work on Travis
+    # system "#{HOMEBREW_PREFIX}/bin/python", "-c", "import moose"
+    system "python", "-c", "import moose"
+  end
+end
diff --git a/macosx/moose_full.xcodeproj/project.pbxproj b/macosx/moose_full.xcodeproj/project.pbxproj
new file mode 100644
index 0000000000000000000000000000000000000000..93fd350d44787252b94c6a9440c831a9a966375a
--- /dev/null
+++ b/macosx/moose_full.xcodeproj/project.pbxproj
@@ -0,0 +1,958 @@
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diff --git a/macosx/port_moose.sh b/macosx/port_moose.sh
new file mode 100755
index 0000000000000000000000000000000000000000..2ea6d0b3aba7393c20d6c95b1ff0aae8ab404927
--- /dev/null
+++ b/macosx/port_moose.sh
@@ -0,0 +1,10 @@
+#!/bin/bash
+# Test the port file.
+set -x
+export PATH=/opt/local/bin:$PATH
+rm -f ~/ports/science/moose/Portfile 
+ln -s `pwd`/Portfile ~/ports/science/moose/Portfile
+( cd ~/ports/ && portindex )
+port lint --nitpick moose
+sudo port uninstall moose
+sudo port -vd  install moose | tee _build_port.log