diff --git a/.ipynb_checkpoints/SSBtoolkit-Tutorial1-checkpoint.ipynb b/.ipynb_checkpoints/SSBtoolkit-Tutorial1-checkpoint.ipynb index d93b89b7239f0ffaee688591ec9ddd12dc9f66ed..feef343d60fe607cb80eccfa44a1cab2de8f620c 100644 --- a/.ipynb_checkpoints/SSBtoolkit-Tutorial1-checkpoint.ipynb +++ b/.ipynb_checkpoints/SSBtoolkit-Tutorial1-checkpoint.ipynb @@ -12,7 +12,7 @@ "\n", "<br><br><br><br>\n", "\n", - "# Simulation of dose-response curves from affinity values\n", + "# Simulation of dose-response curves of agonists using affinity values\n", "\n", "In this tutorial we will simulate a mathematical model of a signaling pathway to obtain dose-response curves, from wich *potency (EC<sub>50</sub>)* values of agonists can be infered. \n", "\n", diff --git a/.ipynb_checkpoints/SSBtoolkit-Tutorial2-checkpoint.ipynb b/.ipynb_checkpoints/SSBtoolkit-Tutorial2-checkpoint.ipynb index f71f5a67187d9f5f3104366b45c745374fce9e90..0e10eb6074ce7090047112b54961f7f33d25f701 100644 --- a/.ipynb_checkpoints/SSBtoolkit-Tutorial2-checkpoint.ipynb +++ b/.ipynb_checkpoints/SSBtoolkit-Tutorial2-checkpoint.ipynb @@ -13,7 +13,7 @@ "<br><br><br><br>\n", "<br>\n", "\n", - "# Simulation of dose-response curves of antagonists\n", + "# Simulation of dose-response curves of antagonists using affinity values\n", "\n", "In this tutorial we will simulate a mathematical model of a signaling pathway to obtain dose-response curves of antagonists, from wich their *potencies (IC$_{50}$)* can be infered. \n", "\n", diff --git a/.ipynb_checkpoints/SSBtoolkit-Tutorial3A-checkpoint.ipynb b/.ipynb_checkpoints/SSBtoolkit-Tutorial3A-checkpoint.ipynb index a752599232446efd32a081d6e47991ffd2649071..b4992fc82ec42de8841b72cafd0fae22b6d05c2e 100644 --- a/.ipynb_checkpoints/SSBtoolkit-Tutorial3A-checkpoint.ipynb +++ b/.ipynb_checkpoints/SSBtoolkit-Tutorial3A-checkpoint.ipynb @@ -13,7 +13,7 @@ "<br><br><br><br>\n", "<br>\n", "\n", - "# Simulation of dose-response curves from kinetic values\n", + "# Simulation of dose-response curves of agonists using kinetic values\n", "\n", "In this tutorial we will simulate mathematical model of a signaling pathway to obtain dose-response curves, and consequently, predict the *efficacy (EC$_{50}$)* of drugs. \n", "\n", diff --git a/.ipynb_checkpoints/SSBtoolkit-Tutorial3B-tauRAMD-checkpoint.ipynb b/.ipynb_checkpoints/SSBtoolkit-Tutorial3B-tauRAMD-checkpoint.ipynb index 7e01490feb1e6daf42366058ed40e3c69db693df..8bfe1aa874490cc2dcfcd79a2807b07e180926de 100644 --- a/.ipynb_checkpoints/SSBtoolkit-Tutorial3B-tauRAMD-checkpoint.ipynb +++ b/.ipynb_checkpoints/SSBtoolkit-Tutorial3B-tauRAMD-checkpoint.ipynb @@ -12,7 +12,7 @@ "<br><br><br><br>\n", "<br>\n", "\n", - "# Simulation of dose-response cruves from data acquired with tauRAMD \n", + "# Simulation of dose-response cruves of agonsits using data acquired with tauRAMD \n", "\n", "\n", "In this notebook we will a simulate mathematical model of a signaling pathway to obtain dose-response curves using kinetic values obtained with the <b>tauRAMD</b> tool.\n", diff --git a/README.md b/README.md index d5855ebc8cc88d414f7e80d793bdc2d78cdc357a..073892372e881e551ee3bff25d796b77b80f9dbb 100644 --- a/README.md +++ b/README.md @@ -25,10 +25,10 @@ What is about: How to do: -1. [Simulation of dose-responses curves from affinity values](SSBtoolkit-Tutorial1.ipynb) -2. [Simulation of dose-responses curves of antagonists](SSBtoolkit-Tutorial2.ipynb) -3. [Simulation of dose-responses curves from kenetic values](SSBtoolkit-Tutorial3A.ipynb) -4. [Simulation of dose-response cruves from data acquired with tauRAMD ](SSBtoolkit-Tutorial3B-tauRAMD.ipynb) +1. [Simulation of dose-response curves of agonists using affinity values](SSBtoolkit-Tutorial1.ipynb) +2. [Simulation of dose-response curves of antagonists using affinity values](SSBtoolkit-Tutorial2.ipynb) +3. [Simulation of dose-response curves of agonists using kenetic values](SSBtoolkit-Tutorial3A.ipynb) +4. [Simulation of dose-response curves of agonists using data acquired with tauRAMD](SSBtoolkit-Tutorial3B-tauRAMD.ipynb) 5. [Exploring SSB pathways associated to disease variants](SSBtoolkit-Tutorial4-OXTR.ipynb) diff --git a/SSBtoolkit-Tutorial1.ipynb b/SSBtoolkit-Tutorial1.ipynb index d93b89b7239f0ffaee688591ec9ddd12dc9f66ed..feef343d60fe607cb80eccfa44a1cab2de8f620c 100644 --- a/SSBtoolkit-Tutorial1.ipynb +++ b/SSBtoolkit-Tutorial1.ipynb @@ -12,7 +12,7 @@ "\n", "<br><br><br><br>\n", "\n", - "# Simulation of dose-response curves from affinity values\n", + "# Simulation of dose-response curves of agonists using affinity values\n", "\n", "In this tutorial we will simulate a mathematical model of a signaling pathway to obtain dose-response curves, from wich *potency (EC<sub>50</sub>)* values of agonists can be infered. \n", "\n", diff --git a/SSBtoolkit-Tutorial2.ipynb b/SSBtoolkit-Tutorial2.ipynb index f71f5a67187d9f5f3104366b45c745374fce9e90..0e10eb6074ce7090047112b54961f7f33d25f701 100644 --- a/SSBtoolkit-Tutorial2.ipynb +++ b/SSBtoolkit-Tutorial2.ipynb @@ -13,7 +13,7 @@ "<br><br><br><br>\n", "<br>\n", "\n", - "# Simulation of dose-response curves of antagonists\n", + "# Simulation of dose-response curves of antagonists using affinity values\n", "\n", "In this tutorial we will simulate a mathematical model of a signaling pathway to obtain dose-response curves of antagonists, from wich their *potencies (IC$_{50}$)* can be infered. \n", "\n", diff --git a/SSBtoolkit-Tutorial3A.ipynb b/SSBtoolkit-Tutorial3A.ipynb index a752599232446efd32a081d6e47991ffd2649071..b4992fc82ec42de8841b72cafd0fae22b6d05c2e 100644 --- a/SSBtoolkit-Tutorial3A.ipynb +++ b/SSBtoolkit-Tutorial3A.ipynb @@ -13,7 +13,7 @@ "<br><br><br><br>\n", "<br>\n", "\n", - "# Simulation of dose-response curves from kinetic values\n", + "# Simulation of dose-response curves of agonists using kinetic values\n", "\n", "In this tutorial we will simulate mathematical model of a signaling pathway to obtain dose-response curves, and consequently, predict the *efficacy (EC$_{50}$)* of drugs. \n", "\n", diff --git a/SSBtoolkit-Tutorial3B-tauRAMD.ipynb b/SSBtoolkit-Tutorial3B-tauRAMD.ipynb index 7e01490feb1e6daf42366058ed40e3c69db693df..8bfe1aa874490cc2dcfcd79a2807b07e180926de 100644 --- a/SSBtoolkit-Tutorial3B-tauRAMD.ipynb +++ b/SSBtoolkit-Tutorial3B-tauRAMD.ipynb @@ -12,7 +12,7 @@ "<br><br><br><br>\n", "<br>\n", "\n", - "# Simulation of dose-response cruves from data acquired with tauRAMD \n", + "# Simulation of dose-response cruves of agonsits using data acquired with tauRAMD \n", "\n", "\n", "In this notebook we will a simulate mathematical model of a signaling pathway to obtain dose-response curves using kinetic values obtained with the <b>tauRAMD</b> tool.\n",