diff --git a/base/requirements.txt b/base/requirements.txt
index 9929e0c05e0521fd9767f225f25d0013859d70cc..bdf4d4155bf68c9e16b9c8aa95b5a5605626024b 100644
--- a/base/requirements.txt
+++ b/base/requirements.txt
@@ -1,7 +1,5 @@
-bluepyopt==1.11.5
 bokeh==2.4.2
 Cython==0.29.26
-ebrains-drive==0.5.0
 h5py==3.6.0
 ipympl==0.8.5
 ipywidgets==7.6.5
@@ -9,14 +7,12 @@ jupyterlab-widgets==1.0.2
 jupyterlab-topbar==0.6.1
 jupyterlab-system-monitor==0.8.0
 jupyterlab-git==0.34.1
-lazyarray==0.5.1
 lxml==4.7.1
 matplotlib==3.5.3
 mpi4py==3.1.3
 nbdime==3.1.1
 nbgitpuller==1.0.2
 nbresuse==0.4.0
-neurom==3.1.0
 nglview==3.0.3
 nibabel==3.2.1
 numba==0.56.4
@@ -27,7 +23,6 @@ patsy==0.5.2
 plotly==5.5.0
 python-swiftclient==3.13.0
 pyOpenSSL==22.0.0 # TODO: Issue with 22.1 https://github.com/pyca/pyopenssl/issues/1154
-pyunicore==0.15.0
 requests-oauthlib==1.3.0
 rise==5.7.1
 rpy2==3.4.5