diff --git a/packages/py-neuroglancer-scripts/package.py b/packages/py-neuroglancer-scripts/package.py
new file mode 100644
index 0000000000000000000000000000000000000000..a2604f78389dc2ab78f733b913fee8046c5d6a09
--- /dev/null
+++ b/packages/py-neuroglancer-scripts/package.py
@@ -0,0 +1,28 @@
+from spack.package import *
+
+
+class PyNeuroglancerScripts(PythonPackage):
+    """Conversion of images to the Neuroglancer pre-computed format"""
+
+    homepage = "https://github.com/HumanBrainProject/neuroglancer-scripts"
+    pypi     = "neuroglancer-scripts/neuroglancer-scripts-1.1.0.tar.gz"
+
+    maintainers = ['Yann Leprince']
+
+    version('1.1.0',    sha256='395a3565808136950a1e3296b43eeda13a0108d2286eba2b2924b33c3b3abc70')
+    version('1.0.0',    sha256='524c0e3a3faebaf3952953f8097af347655bed3e70b3a4bc4043a6f216db7d28')
+    version('1.0.0rc3', sha256='715811702fe4fc88210d54ea913787ab84e17b0ff4b7c62d30130f302a0a8335')
+    version('0.3.0',    sha256='dd85c946f44f5211adf55eba04886e41dc36e9a94c723b966a8485c06d7ed253')
+    version('0.2.0',    sha256='98d906347acf1be6a6cb49ed8753d51776ed38034f395b60de15bcf790e9533c')
+
+    depends_on('python@3.5:',    type=('build', 'run'))
+
+    depends_on('py-nibabel',      type=('build', 'run'))
+    depends_on('py-numpy',        type=('build', 'run'))
+    depends_on('py-pillow',       type=('build', 'run'))
+    depends_on('py-requests',     type=('build', 'run'))
+    depends_on('py-scikit-image', type=('build', 'run'))
+    depends_on('py-tqdm',         type=('build', 'run'))
+
+    # Not needed for the purpose siibra-python
+    # depends_on('py-imagecodecs',  type=('build', 'run')) # TODO: had some issues
diff --git a/packages/py-siibra/package.py b/packages/py-siibra/package.py
new file mode 100644
index 0000000000000000000000000000000000000000..a64b177390a7170a7c6057c0a45dda3becc684ff
--- /dev/null
+++ b/packages/py-siibra/package.py
@@ -0,0 +1,42 @@
+from spack.package import *
+
+
+class PySiibra(PythonPackage):
+    """Software interfaces for interacting with brain atlases"""
+
+    homepage = "https://github.com/FZJ-INM1-BDA/siibra-python"
+    pypi     = "siibra/siibra-0.4a57.tar.gz"
+
+    maintainers = ['x.gui@fz-juelich.de', 's.koehnen@fz-juelich.de', 't.dickscheid@fz-juelich.de']
+
+    version("0.4a57", sha256="53983c4baab84abe5dd6928c320ce87433cab02b5ed992995f0a17661c93dbff")
+    version("0.4a56", sha256="4c03d8a94c73a233e216103fa7090d057db03b1806027fabde38e8f83b852d78")
+    version("0.4a54", sha256="114765afe906383c7e6b930f1df7e26ddc15a6f295e2eab83a861eaba6d8f57f")
+    version("0.4a51", sha256="5aacd53b9b59a98a061c6b95421ab588d35ea7f6f27753c634a42ea7324cf9fe")
+    version("0.4a47", sha256="661b68cd82d4ffbf3f815fb961543cc8c42b695ee601d5856ce90bfc7ccb968a")
+    version("0.4a46", sha256="ddf17cd25c8249111d9f8c0c1088fabcc0fa8796734dc1784506155df6d57568")
+    version("0.4a35", sha256="106a61824c6e3260ee65241add88bbb2d6be4a48756c1e3173860406722a0dc0")
+    version("0.4a33", sha256="d67ba51547cb7fbc792bd14e93d083cabeac978b9a3ee4bfd5cf9aa0c95c5c94")
+    version("0.4a32", sha256="bfeca6c56cc33630a8e046f0ba8a4d9e1168916e64ffe730b4ed08b8ad06bb4c")
+    version("0.4a31", sha256="e49a1583b0b60403d799bca031c05208acd57bf5d3a605cefb3e9439bc36410d")
+    
+    depends_on('python@3.7:',             type=('build', 'run'))
+
+    depends_on('py-anytree',              type=('build', 'run'))
+    depends_on('py-nibabel',              type=('build', 'run'))
+    depends_on('py-appdirs',              type=('build', 'run'))
+    depends_on('py-scikit-image',         type=('build', 'run'))
+    depends_on('py-requests',             type=('build', 'run'))
+    depends_on('py-neuroglancer-scripts', type=('build', 'run'))
+    depends_on('py-nilearn',              type=('build', 'run'))
+    depends_on('py-typing-extensions',    type=('build', 'run'), when='^python@:3.7')
+    depends_on('py-filelock',             type=('build', 'run'))
+
+    depends_on('py-pytest',               type=('test'))
+
+    @run_after('install')
+    @on_package_attributes(run_tests=True)
+    def install_test(self): 
+        pytest = which("pytest")
+        pytest("-rx")
+
diff --git a/spack.yaml b/spack.yaml
index 00edb21f341bb441ad364689fb8474f562b53500..7833039951a60c32437878f245c86a10120eb07f 100644
--- a/spack.yaml
+++ b/spack.yaml
@@ -53,6 +53,7 @@ spack:
     - py-quantities-scidash@0.12.4.3
     - py-quantities@0.14.1
     - py-sciunit@0.2.5.1
+    - py-siibra@0.4a57
     - py-snudda@1.4.0
     - py-tvb-data@2.7
     - py-tvb-framework@2.8.1.1